Adaptation Deviation: It deviates more and more as it goes on, but never too far for it to be a completely new story.Internal sections of the ship that are in a vacuum are changed from life supports failing to pockets of poison gas from The Leviathan.Isaac doesn’t even learn about The Leviathan until encountering an Almost Dead Guy in Mercer’s office who tells him about it before dying. Mercer in order to kill Isaac for getting in the way of his plans.

Chapter 5 as a whole was changed from a mission to mix a poison to kill The Leviathan where Isaac coincidentally meets, and is subsequently antagonized by Dr Mercer and The Hunter, to Isaac responding to a message seemingly sent by Nicole, which turns out to be a trap set up by Dr.

Unfortunately, it doesn't save him from Mercer's treachery, but at least he puts up a fight. He's even packed with a Force Gun to brave the undead halls of the Ishimura. Rather than desperately searching for an SOS beacon in the original game, he's responsible for creating it, as well as many of the traps Isaac finds in the Mining Deck.

Jacob Temple is another downplayed example, being more proactive in the remake.

While he still avoids open combat, he's smart enough to create a modified Stasis module that can completely freeze a person in place for minutes at a time. Here, multiple logs and encounters in sidequests show whole sections of the ship held on substantially longer-presumably either whole days or even weeks-than was believed, with both Medical and the Mining Deck being the last to fall to the relentless infestation, and only because they allowed Mercer to run amok rather than failings on their part in fighting off the Necromorphs.

In the original game, they were all taken off guard by the outbreak aboard the ship in a matter of hours.

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